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Cover for Was beeinflusst die Expression und Wirkung des FOXP2-Gens? Vergleich mit anderen Mitgliedern der FOXP-Familie

Was beeinflusst die Expression und Wirkung des FOXP2-Gens? Vergleich mit anderen Mitgliedern der FOXP-Familie

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كتب واقعية

Der FOXP2-Gen wurde vor allem für seine Sprachfunktion bekannt. Viele Untersuchungen zeigten jedoch, dass FOXP2 auch weitere Prozesse, z.B. Aging, Carcinogenesis, Neurodegeneration reguliert. Diese Arbeit beschäftigt sich mit der Frage, was die Expression und Wirkung des FOXP2-Gens beeinflusst, und geht detaliert auf die Rolle der MiRNA-Modulation, des alternativen Spleißens, der Sumoilierung, Metylierung sowie der Regulation durch PH-Niveau, Vitamin D-Gehalt etc. ein. Dabei wird auch die Struktur und Funktion anderer FoxP-Gene gene beschrieben und über geeignete Tiermodelle zur Untersuchung der FOXP2-Sprachfunktion diskutiert.

© 2021 epubli (كتاب إلكتروني): 9783754111413

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