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Ageless and Timeless with Michele Hughes

In this enlightening episode of Ageless and Timeless, host Michele Hughes welcomes Wade Lightheart, an international health expert, author, and co-founder of BiOptimizers, one of the most trusted supplement companies in the world. Michele—who has personally used and followed BiOptimizers products for years—dives into Wade’s extraordinary journey from professional bodybuilding to becoming a leader in digestive health and human performance.

Wade shares how the tragic loss of his sister to cancer inspired his lifelong pursuit of true wellness. His story takes listeners from the bodybuilding stage, where he appeared to be in peak health but was internally struggling, to his breakthrough discovery about the power of building health from the inside out.This philosophy became the foundation of BiOptimizers—now a global leader in digestive and performance optimization.

Exclusive OfferListeners of Ageless and Timelesscan receive 10% offtheir first BiOptimizers order.Visit bioptimizers.com/agelessfutureor use thecode AGELESS10at checkout.All products come with a 365-day money-back guarantee.

Medical Disclaimer –Ageless and Timeless Podcast

Ageless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

Building the Body from the Inside Out with Wade Lightheart

In this fascinating episode, Michele Hughes sits down with Brian Burzynski, an innovator at the intersection of science, frequency, and physical health. As the creator of Synergy Release Method® (SRM) and the Tension Release Technology™ behind Intelligent Threads, Brian has developed an entirely new approach to structural alignment and wellness —one that allows the body to self-correct through energy-based communication.

Brian shares his personal journey from high school athlete to QuantumEngineering and Mechanics student, where his curiosity about body performance led him to discover how frequency and structure interact. What began as a quest to heal his own injuries evolved into the creation of Intelligent Threads, a line of wearable textiles embedded with microscopic particles that signal muscles to release tension —helping the body return to its natural, balanced state.

Key Topics Discussed
●Brian’s discovery that chronic tension and misalignment stem from compensating muscles—and how releasing them can instantly restore balance.
●The science behind Tension Release Technology™, which uses frequency-encoded particles to communicate with the body’s electrical grid.
●How the body’s energetic field(or aura) interacts with environment, emotion, and posture.
●Real-life success stories —including athletes and everyday people who experienced immediate improvements in pain, posture, and range of motion.
●How Intelligent Threads evolved from Synergy Release Method®to a scalable, wearable solutionhelping thousands improve sleep, reduce inflammation, and enhance recovery.
●The importance of love, forgiveness, and emotional healthin physical healing.

⚡About Intelligent Threads

Born out of the Synergy Release Method®, Intelligent Threadsis the world’s first Tension Release Technology™ textile. Using a proprietary process called molecular fixation, each garment embeds frequency-based particles that communicate directly with the muscular and skeletal systems.Results are often immediate —users report better posture, pain relief, and enhanced recovery within minutes of contact.

Learn more at: IntelligentThreads.com

Products: motherearthlabs.com

Stuart Hover pH balance is what he uses everyday

Wizardsciences.com by Ian Mitchell particularly the Neuro RX and Olympic RX

Activationproducts.comby Ian Clark

What he does is: synergyreleasemethod.com

Docerelifecenter.comDr Kison Frank

Discount code can be Ageless for a 10% discount to your customers.

Medical Disclaimer –Ageless and Timeless PodcastAgeless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.While we strive to featurereputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

The Science of Intelligent Threads: Rebalancing the Body with Frequency and Intention featuring Brian Burzynski, D.PSc.

In this episode of Ageless and Timeless, host Michele Hughes welcomes Dr. Nathan Bryan, one of the world’s leading experts on nitric oxide and its critical role in human health, longevity, and disease prevention.

Michele first met Dr. Bryan at a longevity conference, and since then has admired both his groundbreaking research and his generosity of spirit. She also recently featured him in her monthly editorial column for Top Doctor Magazine, where his work on nitric oxide was highlighted as one of the most important scientific advancements in modern medicine.

Dr. Bryan shares how his career began nearly 30 years ago when nitric oxide was first recognized. Since then, he has made pioneering contributions to understanding how the body produces nitric oxide, what causes deficiencies, and how restoring this essential molecule can improve conditions ranging from cardiovascular disease to dementia.

Today, as Founder, Chairman, and CEO of Bryan Therapeutics, Inc., Dr. Bryan leads multiple clinical-stage programs developing nitric oxide–based therapies for heart disease, Alzheimer’s, and diabetic ulcers. His consumer line of nitric oxide products has also become one of the most trusted on the market.

In This Episode, You’ll Learn:
●Why nitric oxide is considered the “foundation of health” and essential for cardiovascular, metabolic, and cognitive function.
●How nitric oxide production impacts blood flow, mitochondrial function, stem cell mobilization, and telomere health.
●The reasons common supplements like L-arginine and L-citrulline often fail to restore nitric oxide.
●How lifestyle habits such as nasal breathing, oral hygiene, and diet affect nitric oxide production.
●Why nitric oxide may hold the key to treating conditions like Alzheimer’s, diabetes, hypertension, and erectile dysfunction

Dr. Bryan’s passion for science and commitment to developing both safe consumer products and FDA-approved therapies is transforming how we think about health and longevity.
Learn more about Dr. Bryan’s work:
●N1O1.com
●DrNathanSBryan.com
●BryanTherapeutics.com

Follow Dr. Bryan on Instagram @drnathansbryan and Twitter @drnitric.

✨Don’t miss Michele’s article featuring Dr. Bryan in Top Doctor Magazine

Medical Disclaimer –Ageless and Timeless PodcastAgeless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content

Dr nathan bryan

In this inspiring episode of Ageless & Timeless, Michele Hughes welcomes her dear
friend, Lisa Tamati — a world-renowned ultra-endurance athlete, author, coach, and
biotech entrepreneur.

Lisa spent 25 years racing in the toughest endurance events on Earth, from the
Himalayas to Death Valley, covering over 70,000 km and surviving expeditions including
an illegal crossing of the Libyan Desert. Her journey embodies resilience, grit, and
determination, and she shares how these experiences shaped her drive to help others
unlock their potential.

Lisa’s story goes far beyond athletics. When her mother suffered a devastating brain
aneurysm, Lisa’s relentless research and unconventional protocols helped her recover
against all odds. Later, when her mother was diagnosed with brain cancer, Lisa once
again defied the prognosis, combining integrative medicine, advanced therapies, and
unwavering tenacity to extend and improve her mother’s life.

Today, Lisa channels her expertise into coaching, podcasting, and her biotech ventures,
including the development of Cellular Restore, a groundbreaking formulation targeting
immune system aging. She also created an immune age calculator designed to give
individuals and practitioners deeper insights into immune health and longevity.
Together, Michele and Lisa discuss:

● How Lisa’s endurance racing career taught her to overcome adversity and “push
the limits.”
● The turning point that set her on a mission to advocate for health sovereignty.
● The powerful role of hyperbaric oxygen therapy and functional medicine in brain
recovery.
● Her latest work in biotech and longevity, including immune system support and
innovation.
● Why becoming the CEO of your own health is essential in today’s medical
landscape.

Lisa’s journey is a masterclass in courage, determination, and self-empowerment.

About Lisa Tamati:

Lisa Tamati is a former professional ultra-endurance athlete, keynote speaker, author,
health coach, and biotech entrepreneur. She is the author of five books, including
international bestsellers Running Hot and Running to Extremes, and the host of Pushing
the Limits, a top 200 global podcast in health, functional medicine, and longevity. She
has been honored as Māori Sportswoman of the Year and has earned national and
international podium finishes. Today, Lisa’s mission is to help others achieve their
highest potential in health, performance, and life.

Resources & Links:
● Learn more about Lisa Tamati: lisatamati.com
● Listen to Pushing the Limits: available on all major podcast platforms
● Explore Cellular Restore (US) / Rejuvenate Pro (NZ): [link to product/distributor]
● Follow Lisa on YouTube: Lisa Tamati Channel

Medical Disclaimer – Ageless and Timeless Podcast
Ageless and Timeless (the “Show”), along with its host and guests, shares insights and
discussions on health, wellness, and longevity for informational and educational
purposes only. The Show does not provide medical advice, diagnoses, treatments,
cures, or preventative recommendations for any disease or health condition. The
content shared should not be used as a substitute for professional medical advice,
diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither
Ageless and Timeless nor its host or affiliates assume responsibility for errors,
omissions, or misinterpretations in the information provided. Listeners are encouraged
to use their own discretion and consult with a licensed medical professional before
making any health-related decisions. By listening to this podcast, you acknowledge that
any actions you take based on the information presented are at your own risk, and
Ageless and Timeless, its host, guests, and affiliates are not liable for any direct,
indirect, incidental, or consequential damages resulting from the use of this content.

Pushing the Limits with Lisa Tamati: Resilience, Health, and the Power of Never Giving Up

In this episode, Michele Hughes sits down with Dr. Joseph Purita, widely regarded as a
pioneer in orthopedic regenerative medicine. With decades of experience as a board-
certified orthopedic surgeon and inaugural president of the American Academy & Board
of Regenerative Medicine, Dr. Purita has helped shape the future of cellular and anti-
aging therapies.

What You’ll Learn in This Episode:

● The Evolution of Regenerative Medicine: How Dr. Purita moved from traditional
orthopedic surgery to leading the way in platelet-rich plasma (PRP), stem cells,
and advanced cellular therapies.

● PRP, Exosomes & Regenerative “Soup”: Why platelets are far more than clotting
agents, and how exosomes and growth factors work as nature’s true healers.

● Photobiomodulation & Red Light Therapy: How light wavelengths can rejuvenate
cells, enhance stem cell survival, and be applied for both clinical and at-home
use.

● Hyperbaric Oxygen & EBO₂ Therapy: The science behind oxygenating and
ozonating the blood to release stem cells, reduce inflammation, and detoxify the
body.

● NAD, Supplements & Anti-Aging Protocols: Why intravenous NAD remains a
gold standard, how to maximize its effectiveness, and which supplements Dr.
Purita personally recommends for longevity.

● Intermittent Hypoxia & Mitochondrial Health: Exploring altitude training in a chair,
telomere research, and how therapies like hydrogen water and phosphatidylcholine support cellular resilience.

● Gut-Brain Connection & Longevity: The critical role of gut health, probiotics, and
supplements in maintaining cognitive function and overall vitality.

● The Future of Longevity Medicine: Dr. Purita’s perspective on how regenerative
medicine and AI will accelerate breakthroughs in the next five years.

About Dr. Purita

Dr. Joseph Purita received his medical degree from Georgetown University and
completed his orthopedic residency at the University of Miami. He is internationally
recognized for pioneering work in regenerative medicine, with practices in Boca Raton,
the Cayman Islands, and global collaborations. As Chief Medical Officer of PurForm
Health, he continues to expand access to cutting-edge treatments that blend orthopedic
innovation with anti-aging science.

Resources & Links
● Learn more about Dr. Purita: PurForm Health
● Call for a free consult (with code Ageless): 561-368-1880
● Email: info@purformhealth.com

● Follow Michele Hughes: Ageless &Timeless: YouTube, Instagram @agelessandtimeless

Medical Disclaimer – Ageless and Timeless Podcast

Ageless and Timeless (the “Show”), along with its host and guests, shares insights and
discussions on health, wellness, and longevity for informational and educational
purposes only. The Show does not provide medical advice, diagnoses, treatments,
cures, or preventative recommendations for any disease or health condition. The
content shared should not be used as a substitute for professional medical advice,
diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither
Ageless and Timeless nor its host or affiliates assume responsibility for errors,
omissions, or misinterpretations in the information provided. Listeners are encouraged
to use their own discretion and consult with a licensed medical professional before
making any health-related decisions. By listening to this podcast, you acknowledge that
any actions you take based on the information presented are at your own risk, and
Ageless and Timeless, its host, guests, and affiliates are not liable for any direct,
indirect, incidental, or consequential damages resulting from the use of this content.

Regenerative Medicine & Longevity: Dr. Joseph Purita on Healing from the Inside Out

In this episode of Ageless and Timeless, host Michele Hughes welcomes Dr. Ken Davis,
founder of the Davis Advanced Health System. With over 48 years in private practice,
Dr. Davis has developed a unique, integrative, and preventative system that blends
advanced chiropractic procedures, craniopathy, sacro-occipital technique, soft tissue
orthopedics, applied kinesiology, vibrational therapy, and clinical nutrition. His methods
go far beyond the traditional adjustment—addressing the whole person through the triad
of physical, mental, and spiritual well-being.

Dr. Davis shares his remarkable journey from aspiring dentist to renowned chiropractor
and educator, including the pivotal mentors and life events that shaped his path. He
explains his "Triangle of Well-Being" philosophy, the importance of identifying the root
cause of illness, and the role of muscle testing in uncovering hidden emotional and
spiritual blocks. Listeners will also learn about Natural Force Healing, a vibrational
energy system he co-developed that can release trauma, balance the nervous system,
and restore vitality.

Beyond his clinical expertise, Dr. Davis inspires with his personal
transformation—taking up competitive bodybuilding at age 66, writing bestselling books,
and continuing to mentor practitioners worldwide. This conversation is packed with
wisdom for anyone seeking a deeper, more holistic approach to health and longevity.

Medical Disclaimer – Ageless and Timeless Podcast

Ageless and Timeless (the “Show”), along with its host and guests, shares insights and
discussions on health, wellness, and longevity for informational and educational
purposes only. The Show does not provide medical advice, diagnoses, treatments,
cures, or preventative recommendations for any disease or health condition. The
content shared should not be used as a substitute for professional medical advice,
diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither
Ageless and Timeless nor its host or affiliates assume responsibility for errors,
omissions, or misinterpretations in the information provided. Listeners are encouraged
to use their own discretion and consult with a licensed medical professional before
making any health-related decisions. By listening to this podcast, you acknowledge that
any actions you take based on the information presented are at your own risk, and
Ageless and Timeless, its host, guests, and affiliates are not liable for any direct,
indirect, incidental, or consequential damages resulting from the use of this content.

Body, Mind, and Spirit: The Davis Advanced Health System with Dr. Ken Davis

In this energizing episode, Michele Hughes sits down with Dr. Robert Weil—also known as “The Sports Doctor”—to explore the powerful connection between foot health, athletic performance, and longevity. With over 40 years of clinical and radio experience, Dr. Weil shares stories from his work with elite athletes, Olympic figure skaters, and weekend warriors, shedding light on how podiatry plays a vital role in injury prevention, performance enhancement, and overall wellness.From the epidemic of youth sports overuse injuries to the rise of complementary medicine and functional fitness, Dr. Weil brings humor, science, and heart to a conversation that touches everyone—whether you're a grandparent chasing grandkids or a pickleball enthusiast chasing a ball. He offers practical tips for strengthening feet and ankles, discusses the mental game in sports and life, and explains why orthotics can be a game changer.

Medical Disclaimer –Ageless and Timeless PodcastAgeless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

The Sports Doctor Is In: Ageless Wisdom from the Ground Up

In this energizing episode, Michele Hughes sits down with Dr. Robert Weil—also known as “The Sports Doctor”—to explore the powerful connection between foot health, athletic performance, and longevity. With over 40 years of clinical and radio experience, Dr. Weil shares stories from his work with elite athletes, Olympic figure skaters, and weekend warriors, shedding light on how podiatry plays a vital role in injury prevention, performance enhancement, and overall wellness.

From the epidemic of youth sports overuse injuries to the rise of complementary medicine and functional fitness, Dr. Weil brings humor, science, and heart to a conversation that touches everyone—whether you're a grandparent chasing grandkids or a pickleball enthusiast chasing a ball. He offers practical tips for strengthening feet and ankles, discusses the mental game in sports and life, and explains why orthotics can be a game changer.

Medical Disclaimer

–Ageless and Timeless PodcastAgeless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

In this powerful return episode, Michele Hughes welcomes back Ryan Smith, founder and Chief Scientific Officer of TruDiagnostic. Formerly the CEO of Tailor Made Compounding, Ryan transitioned his focus from peptides to epigenetic science, becoming a leading force in the field of biological aging. This episode is a deep-dive tutorial on biological age testing, DNA methylation, and how epigenetics can give us control over the aging process.

Ryan explains the difference between chronological and biological age, the power of DNA methylation data, and the cutting-edge technology behind TruDiagnostic’s comprehensive testing. Listeners will also learn about telomeres, organ-specific age reports, and the groundbreaking “Rejuvenation Olympics.” Michele shares her own test results and explores how these tools offer insight into one’s aging trajectory and risk factors for chronic disease.

Whether you’re new to biohacking or a longevity enthusiast, this episode offers a front-row seat to the future of preventative health.

🧬 Topics Covered: • Ryan’s journey from medical school dropout to peptide pioneer and scientific director
 • What peptides and peptide bioregulators really are
 • Understanding epigenetic clocks and why biological age matters more than chronological
 • The science of DNA methylation and how it measures gene expression
 • Differences between traditional DNA tests and epigenetic testing
 • Why telomere testing is outdated and less predictive
 • What TruDiagnostic’s tests reveal—from organ system age to personalized healthspan insights
 • Data-driven interventions for slowing and reversing aging
 • How TruDiagnostic’s “TrueHealth” report may soon replace traditional blood tests
 • Clinical trials, FDA approval pathways, and the future of aging diagnostics
🔗 Learn More & Order a Test:

Visit www.trudiagnostic.com and use code AGELESS20 for 20% off.
Connect with Ryan Smith on LinkedIn for more insights and research updates.

Medical Disclaimer – Ageless and Timeless PodcastAgeless and Timeless (the “Show”), along with its host and guests, shares insights and discussions on health, wellness, and longevity for informational and educational purposes only. The Show does not provide medical advice, diagnoses, treatments, cures, or preventative recommendations for any disease or health condition. The content shared should not be used as a substitute for professional medical advice, diagnosis, or treatment.While we strive to feature reputable sources and knowledgeable guests, neither Ageless and Timeless nor its host or affiliates assume responsibility for errors, omissions, or misinterpretations in the information provided. Listeners are encouraged to use their own discretion and consult with a licensed medical professional before making any health-related decisions. By listening to this podcast, you acknowledge that any actions you take based on the information presented are at your own risk, and Ageless and Timeless, its host, guests, and affiliates are not liable for any direct, indirect, incidental, or consequential damages resulting from the use of this content.

Reversing Age with Science: Ryan Smith on Epigenetics, Peptides, and the Future of Longevity

In this deeply informative and wide-ranging episode of Ageless and Timeless, host
Michele Hughes welcomes Dr. Kent Holtorf, a pioneering medical innovator in peptide
and longevity science. Dr. Holtorf shares his extraordinary journey from debilitating
illness to breakthrough recovery, and how it led to his revolutionary work in biohacking,
personalized medicine, and integrative therapies.

Together, Michele and Dr. Holtorf explore:

● The critical difference between peptides and peptide bioregulators
● Protocols for reversing chronic conditions, autoimmune diseases, and
neurodegenerative decline
● Why conventional medicine lags 10–20 years behind current research
● How strategic peptide stacking heals the gut, reduces inflammation, boosts
mitochondrial health, and rewires immunity
● The science and safety behind GLP-1s like Ozempic and how to optimize
outcomes by pairing them with follistatin

Plus, Dr. Holtorf offers exclusive insight into personalized treatment approaches using
true diagnostic testing and epigenetic biomarkers. As a special bonus, listeners get 25%
off products from Integrative Peptides using code AGELESS25 at
integrativepeptides.com.

Medical Disclaimer – Ageless and Timeless Podcast
Ageless and Timeless (the “Show”), along with its host and guests, shares insights and
discussions on health, wellness, and longevity for informational and educational
purposes only. The Show does not provide medical advice, diagnoses, treatments,
cures, or preventative recommendations for any disease or health condition. The
content shared should not be used as a substitute for professional medical advice,
diagnosis, or treatment.

While we strive to feature reputable sources and knowledgeable guests, neither
Ageless and Timeless nor its host or affiliates assume responsibility for errors,
omissions, or misinterpretations in the information provided. Listeners are encouraged
to use their own discretion and consult with a licensed medical professional before
making any health-related decisions. By listening to this podcast, you acknowledge that
any actions you take based on the information presented are at your own risk, and
Ageless and Timeless, its host, guests, and affiliates are not liable for any direct,
indirect, incidental, or consequential damages resulting from the use of this content.

Peptides, Bioregulators, and the Future of Medicine with Dr. Kent Holtorf

William John Azzalino is a Nationally awarded developmental architect. He was bornApril 1st, 1950 in South Western Wisconsin to the parents of John and Viola Azzalino. … He graduated from the University of Wisconsin with a Bachelors of Science in 1972 and a Masters of Architecture, Magna Cum Laude, in 1974.

William Azzalino, Nationally awarded developmental architect

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