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Descubre un mundo infinito de historias

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BBC Radio 4

A weekly programme that illuminates the mysteries and challenges the controversies behind the science that's changing our world.

BBC Inside Science

This week, a world first gene therapy treats rare Hunter syndrome. Could these personalised medicines be used more widely? We speak to Claire Booth, professor in Gene Therapy at Great Ormond Street Hospital. 

And high in the Chilean desert, the last bit of 13 billion year old light has hit the mirror of the Atacama Cosmology Telescope for the last time. Dr Jenifer Millard, a science communicator and host of the Awesome Astronomy podcast, tells us what it’s been up to for the past 20 years.

And Penny Sarchet, managing editor at New Scientist brings her pick of the latest new discoveries.

Think you know space? Head to bbc.co.uk, search for BBC Inside Science, and follow the links to the Open University to try The Open University Space Quiz. 

Presenter: Tom Whipple
Producers: Alex Mansfield, Ella Hubber, Jonathan Blackwell, Tim Dodd and Clare Salisbury
Editor: Martin Smith
Production Co-ordinator: Jana Bennett-Holesworth

Why aren’t gene therapies more common?

COP 30 delegates from around the globe are about to depart the Amazon city of Belem in Brazil. But not before some very important documents are drawn up. Camilla Born, former advisor to Cop 26 president Alok Sharma speaks to Tom Whipple about the scientific significance of the language negotiators choose to use. 

And it’s the eve of The Ashes. As England Men’s Cricket Team line up against their Australian counterparts in Perth, cricket fans on both sides will be hoping for sporting records to fall. But is breaking those records getting increasingly less likely? And can some maths explain all? Tom asks Kit Yates, author and Professor of Mathematical Biology and Public Engagement at the University of Bath.

Plus science broadcaster Caroline Steel is in the studio to discuss this week’s brand new scientific discoveries. 

If you want to test your climate change knowledge, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University to take the quiz. 

Presenter: Tom Whipple
Producers: Jonathan Blackwell, Ella Hubber, Tim Dodd, Alex Mansfield and Clare Salisbury
Editor: Martin Smith
Production Co-ordinator: Jana Bennett-Holesworth

What’s in the wording of the COP 30 negotiations?

This week the UK government set out its vision for a world where the use of animals in science is eliminated in all but exceptional circumstances. Animal experiments in the UK peaked at 4.14 million in 2015 driven mainly by a big increase at the time in genetic modification experiments. By 2020, the number had fallen sharply to 2.88 million as alternative methods and technologies were developed. But since then that decline has plateaued. 

Could we see the end of animals being used in science labs? Presenter Tom Whipple is joined by Dr. Chris Powell, Director of Cambridge BioPharma Consultants Ltd. and honorary visiting scientist at Cambridge University and Dr. Natalie Burden, head of New Approach Methodologies at the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs). 

And as world leaders gather for the COP30 climate conference in Brazil, we speak to glaciologist Dr. Matthias Huss. In the past decade, his data has shown that a quarter of Swiss ice has been lost, with hundreds of glaciers having disappeared entirely. But part of one of those glaciers remains in the freezer of his basement... 

Also Penny Sarchet, managing editor at New Scientist, brings us her take on the new science that matters this week. 

To discover more fascinating science content, head to bbc.co.uk, search for BBC Inside Science and follow the links to The Open University. 

Presenter: Tom Whipple 
Producers: Clare Salisbury, Tim Dodd, Alex Mansfield, Jonathan Blackwell 
Editor: Martin Smith 
Production Co-ordinator: Jana Bennett-Holesworth

Could technology replace animal testing in science?

Astronomers have new evidence, which could change what we understand about the expansion of the universe. Carlos Frenk, Ogden Professor of Fundamental Physics at Durham University gives us his take on whether the dark energy pushing our universe apart is getting weaker.

With the Turing Prize, the Nobel Prize and now this week the Queen Elizabeth Prize for Engineering under his belt, Geoffrey Hinton is known for his pioneering work on AI. And, since leaving a job at Google in 2023, for his warnings that AI could bring about the end of humanity. Tom Whipple speaks to Geoffrey about the science of super intelligence. 

And Senior physics reporter at Nature Lizzie Gibney brings us her take on the new science that matters this week.

To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

Presenter: Tom Whipple 
Producer: Clare Salisbury
Content Producer: Ella Hubber
Assistant Producers: Jonathan Blackwell & Tim Dodd
Editor: Martin Smith
Production Co-ordinator: Jana Bennett-Holesworth

Is Dark Energy Getting Weaker?

What’s been called the storm of the century - Hurricane Melissa – has barrelled through Jamaica, Cuba, and the Bahamas over the past two days. Hannah Cloke, Professor of Hydrology at the University of Reading, explains whether Melissa was caused – or made worse - by human-made climate change. 

As the H5N1 bird flu season picks up across British farms, virologist Ian Brown from the Pirbright Institute assesses its threat and turns our attention to a largely ignored strain of bird flu – H9N2 – which a recent study suggests is becoming adapted to human cells. 

The interstellar comet 3I/Atlas has inspired some bizarre theories about alien life coming into our solar system. BBC science journalist Roland Pease, who has been watching these cosmic events and the pseudoscientific myths that follow in their wake for decades, gives us his take. 

And mathematician Katie Steckles brings us her favourite finds from the world of science.

If you want to test your climate change knowledge, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University to take the quiz.

Presenter: Victoria Gill 
Producers: Ella Hubber, Jonathan Blackwell, Tim Dodd
Editor: Martin Smith
Production Co-ordinator: Jana Bennett-Holesworth

Is climate change to blame for Hurricane Melissa?

The 'bionic eye' may make you think of Star Trek’s Geordi La Forge. Now, scientists have restored the ability to read in a group of blind patients with advanced dry age-related macular degeneration (AMD). And they’ve done it by implanting a computer chip in the back of their eyes. Professor Francesca Cordeiro, Chair of Ophthalmology at Imperial College London explains how bionic technology might provide future solutions for more people with sight loss.

Researchers at the University of Sheffield have come up with a way of extracting hormones from human remains dating as far back as the 1st century AD. Marnie Chesterton speaks to Brenna Hassett, bioarchaeologist at the University of Lancashire to find out how pregnancy testing skeletons could cast new information on human evolution. 

In a world of automation and AI, its easy to forget that every day, people around the UK record weather observations which contribute to our understanding of climate science. Marnie meets Met Office volunteer Stephen Burt and climate scientist at the University of Reading, Professor Ed Hawkins to find out more. And science broadcaster Caroline Steel brings us brand new discoveries changing the way we understand the world around us.

If you want to find out more about volunteering to collect rain data, you can email: nationalhydrology@environment-agency.gov.uk. If you’re in Scotland, visit the SEPA website: https://www2.sepa.org.uk/rainfall/GetInvolved

To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

Presenter: Marnie Chesterton 
Producer(s): Clare Salisbury, Ella Hubber, Jonathan Blackwell, Tim Dodd
Editor: Martin Smith
Production Coordinator: Jana Holesworth

Have scientists created a bionic eye?

Inside Science explores the science and maths of games: why we play them, how to win them and the rise of gamification in our lives - with a particular focus on The Traitors - in a special programme with a live audience at Green Man Festival in the Bannau Brycheiniog (Brecon Beacons) National Park. 

Presenter Victoria Gill looks into whether humans are innately programmed to play games with Gilly Forrester, professor of evolutionary and developmental psychology at the University of Sussex, and investigates how maths can help us strategise and win games with mathematician and maths communicator Dr Katie Steckles.

We encounter the Prisoner’s Dilemma with broadcaster Jaz Singh of The Traitors series 2 fame – will he share or steal? Jaz also dives into the immersive world of The Traitors discussing his gameplay, the stakes and what makes an effective Faithful!

To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

Presenter: Victoria Gill 
Producers: Jonathan Blackwell and Clare Salisbury 
Editor: Martin Smith 
Production Co-ordinator: Jana Bennett-Holesworth

Why do we love to play games?

This week, renewables overtake coal as the world’s biggest source of electricity. China is leading the renewable charge despite its global reputation as a coal burning polluter. Zulfiqar Khan, Visiting Professor at Bournemouth University and Tsinghua University in Beijing and Furong Li, Professor in the department of Electrical Engineering at the University of Bath explain what China is getting right and what UK science can learn.

The 2025 Nobel Prize winners have just been announced. The prize for physics has been awarded “for the discovery of macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit.” But what does that mean? Science journalist and author Phil Ball explains how the winning quantum engineering experiments in the 1980s laid the groundwork for devise used in today’s quantum computers.

Comedian Josie Long finds escapism in extinct megafauna. She speaks to Marnie Chesterton about her new stand up tour ‘Now is the Time of Monsters’. And Managing Editor for the new Scientist Penny Sarchet brings us her pick of the week’s most important new scientific discoveries. 

To discover more fascinating science content, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University.

Presenter: Marnie Chesterton
Producer: Clare Salisbury
Content Producer: Ella Hubber
Assistant Producer: Jonathan Blackwell
Editor: Martin Smith
Production Co-ordinator: Jana Bennett-Holesworth

What can the UK learn from China on renewable energy?

Scientists in the US have, for the first time, made early-stage human embryos by manipulating DNA taken from people's skin cells and then fertilising them with sperm. It’s hoped the technique could overcome infertility due to old age or disease. 

Marnie Chesterton is joined by Dr Geraldine Jowett from the University of Cambridge and Emily Jackson from the London School of Economics to discuss the science behind the research, and the ethical and legal issues it could raise. 

We also look back at the life of the pioneering primatologist and conservationist Jane Goodall, who died this week at the age of 91. Marnie is joined by one of the scientists she helped to inspire - the biologist Joyce Poole - to reflect on the huge legacy she leaves behind. 

As the European Union discusses the possibility of setting up a Europe-wide ‘drone wall’ to protect against Russian airspace incursions, we discuss the rapid advancements in drone technology with journalist and author of the book ‘Swarm Troopers: How Small Drones Will Conquer The World’, David Hambling. 

And Marnie is joined by journalist Caroline Steel to look through a range of this week’s most intriguing scientific breakthroughs. 

Presenter: Marnie Chesterton 
Producers: Clare Salisbury, Ella Hubber, Dan Welsh, Jonathan Blackwell, Tim Dodd 
Editor: Martin Smith 
Production Co-ordinator: Jana Bennett-Holesworth

Are embryos made from skin cells the future of fertility treatment?

What do we know about the causes of autism? Laura Andreae, Professor of Developmental Neuroscience at King’s College London explains the science. It’s after President Trump made unproven claims the condition is linked to taking paracetamol in pregnancy.

Tim O’Brien, Professor of Astrophysics at The University of Manchester and Associate Director of Jodrell Bank Centre, explains why NASA is planning to send a crew of astronauts around the moon for the first time in 50 years.

Tim Minshall, inaugural Dr John C. Taylor Professor of Innovation at the University of Cambridge dives into the mysterious world of manufacturing. His book ‘Your Life is Manufactured’ is shortlisted for the Royal Society Trivedi Science Book Prize 2025. And we hear from Dave Sexton, conservationist on the Isle of Mull, and his search for one unusual bird.

If you want to test your climate change knowledge, head to bbc.co.uk search for BBC Inside Science and follow the links to The Open University to take the quiz.

Could technology replace animal testing in science?

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