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What does exercise do to your brain? Can psychedelics treat depression? From smart daily habits to new medical breakthroughs, welcome to TED Health, with host Dr. Shoshana Ungerleider. TED speakers answer questions you never even knew you had, and share ideas you won't hear anywhere else, all around how we can live healthier lives.

Follow Dr. Shoshana Ungerleider on Instagram at @shoshanamd and LinkedIn at @shoshanaungerleidermd

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TED Health

TED Health's very own Dr. Shoshana Ungerleider has a new podcast Before We Go. You heard the first episode earlier this year so we wanted to share the second episode in the series -- if you'd like more from Before We Go, check it out wherever you are listening to this.

Before We Go follows Shoshana's personal and emotionally charged journey after her father was diagnosed with terminal cancer in the summer of 2022. His doctors were encouraged when testing showed that the cancer was related to a BRCA genetic mutation, which meant that it might respond to new, targeted therapies. But that also meant that Shoshana and her sister were also at risk for developing life-threatening cancers. With the help of renowned experts and some of the professionals who helped her along the way, Shoshana tells her story of love, loss, family, mortality, and the unexpected paths we take to find meaning and purpose in the face of life's greatest challenges.

In this episode, Shoshana reflects on the death of her paternal grandmother, Joy Ungerleider, who died of the same cancer Steven now faces. The family learns that Steven's cancer is BRCA-related, and hope rises with the possibility that targeted therapy may offer him many months, if not years, of quality life. But he would first need to endure several months of harsh chemotherapy. See behind the scenes and join the conversation on Instagram @beforewegopodcast.

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A special episode from Before We Go

Could the next wonder drug be somewhere in Canada's snowy north? This week, we’re revisiting a talk that takes us to a breathtakingly frigid landscape, where chemist Normand Voyer uncovers the mysterious molecular treasures hidden within plants that thrive in the cold. These scarcely investigated organisms could hold immense medical promise, he says — so long as we work quickly enough to discover them.

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Are life-saving medicines hiding in the world's coldest places? | Normand Voyer

We may think the complexities of the human mind can only be understood by other humans. Yet research on chatbots and psychology suggests non-human bots can actually help improve mental health. In this episode of The TED AI show, another podcast from the TED Audio Collective, host Bilawal Sidhu talks with Dr. Alison Darcy, the founder of mental health app Woebot, and Brian Chandler, an app user, to learn what chatbots reveal about our inner lives and what they can (and can’t) do when it comes to emotional wellness.

Check out the 99% Invisible episode we reference in the episode here: https://99percentinvisible.org/episode/the-eliza-effect/ 

For transcripts for The TED AI Show, visit go.ted.com/TTAIS-transcripts 

Find more of The TED AI Show wherever you get your podcasts.

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The TED AI Show: AI therapy is here. What does it mean for you?

Legendary actor and mental health advocate Glenn Close is on a quest to change how we think about mental health, starting with her decision to speak out about her own family's struggles — a brave choice considering the stigma that pervades the topic. This week, we're revisiting this sweeping conversation with TEDWomen curator Pat Mitchell, where Close shares the inspiration behind the advocacy group she founded to combat the crisis, underscoring the transformative power of community and the critical need for comprehensive mental health care systems.

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My mission to change the narrative of mental health | Glenn Close

What if animals like dogs, ferrets, mice and raccoons could help sniff out the next pandemic? Exploring the science of smell, neurobiologist Glen J. Golden delves into the development of a "mechanical nose" that could detect diseases by identifying specific odor profiles. Until that technology is fully developed, he explains how we can train humanity's furry allies to identify illnesses — and help stop the spread in its tracks.

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Can dogs detect the next pandemic before it begins? | Glen J. Golden

In the 5th century, a shipmaster was suffering from a nasty infection that caused his jaws to press together, his teeth to lock up, and the muscles in his neck and spine to spasm. Today we know this account to be one of the first recorded cases of tetanus. So, what causes this peculiar infection? Louise Thwaites explores how tetanus affects our bodies, and how we can prevent it. This lesson was directed by Andrew Foerster, Rewfoe, narrated by Pen-Pen Chen and the music is by Jason Stamatyades.

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Why is it so dangerous to step on a rusty nail? | Louise Thwaites

We all know a good night’s sleep is essential, but for many people, sleeping well (or falling asleep at all) can be difficult and even stressful – and there’s no shortage of tales about what prevents people from catching their ZZZs. In this episode of Body Stuff with Dr. Jen Gunter, Dr. Jen digs into "how to sleep'' culture – from blue light blockers to sleep hygiene enthusiasts, to the 8 hours a night rule to… witches?! Don’t sleep on this episode–because it might just have you skipping the melatonin supplements and rethinking sleep rituals – before jumping into bed for a well-deserved snooze. Read the full transcript for this episode at https://go.ted.com/BSTscript11

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Do you really need 8 hours of sleep? | Body Stuff with Dr. Jen Gunter

It's time to make psychiatry more psychedelic, says psychiatrist Benjamin Lewis. Sharing results from his clinical trial on psychedelic-assisted therapy, he highlights how group therapy paired with the safe use of psilocybin, a compound found in magic mushrooms, has the potential to improve mental health conditions like depression and burnout. After the talk, Dr. Anthony Back, a palliative care physician, joins Shoshana to discuss his study on using psilocybin-assisted therapy to treat burnout among frontline healthcare workers.

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Could psychedelics help patients in therapy? | Benjamin Lewis

What we eat is less about what we choose and more about what’s offered to us, says food and climate expert Sarah Lake. Unpacking how governments and companies have driven up meat consumption in the US through extensive marketing, she explains how we could employ these same forces to incentivize plant-based eating — for the sake of the planet, public health and global food security.

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The hidden forces behind your food choices | Sarah Lake

Data isn’t just about numbers or trends — it’s about capturing the stories that shape our lives, says information designer Giorgia Lupi. Following a long COVID diagnosis, she tracked her symptoms meticulously over four years, the data culminating in a visual “New York Times” narrative that resonated deeply with many others suffering from chronic illness. Lupi invites us to consider data not as a rigid or objective truth, but as a living language used to better understand ourselves, offering a surprising shift in perspective — depending on where you look.

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What long COVID taught me about life (and data) | Giorgia Lupi

You've probably heard of CRISPR, the revolutionary technology that allows us to edit the DNA in living organisms. Biochemist and 2023 Audacious Project grantee Jennifer Doudna earned the Nobel Prize for her groundbreaking work in this field — and now she's here to tell us about its next world-changing advancement. She explains how her team at the Innovative Genomics Institute is pioneering a brand new field of science — precision microbiome editing — that uses CRISPR in an effort to solve seemingly insurmountable problems like asthma, Alzheimer's and climate change. This ambitious idea is part of the Audacious Project, TED's initiative to inspire and fund global change.

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CRISPR's next advance is bigger than you think | Jennifer Doudna

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