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All-In Podcast

Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.

All-In with Chamath, Jason, Sacks & Friedberg

(0:00) Bestie intros!
 
(1:53) EA acquired for $55B in biggest LBO ever, why PE is in trouble
 
(17:42) IPO market, SPAC 2.0
 
(27:41) The AI rollup opportunity
 
(36:01) Sacks joins the show!
 
(38:27) OpenAI and Meta launch short-form video apps: "AI Slop" or the future of content?
 
(45:04) Open source AI: DeepSeek's new model, pressure on US AI industry
 
(1:05:11) State AI regulation frenzy: States' rights vs Federal control, overregulation
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg
 
Intro Video Credit:
 
https://x.com/TheZachEffect
 
Referenced in the show:
 
 https://apnews.com/article/ea-electronic-arts-video-game-silver-lake-pif-d17dc7dd3412a990d2c0a6758aaa6900
 
 https://www.ign.com/articles/xbox-game-pass-ultimate-price-rises-to-30-a-month-microsoft-adds-more-day-one-games-and-throws-in-fortnite-crew-and-ubisoft-classics-to-help-justify-the-cost
 
https://x.com/Jason/status/1973461806585966655
 
 https://www.npr.org/2025/09/05/nx-s1-5529404/anthropic-settlement-authors-copyright-ai
 
https://x.com/scaling01/status/1972650237266465214
 
 https://www.insidetechlaw.com/blog/2025/09/californias-transparency-in-frontier-artificial-intelligence-act
 
 https://www.datacenterdynamics.com/en/news/google-withdraws-rezoning-proposal-for-468-acre-data-center-project-in-franklin-township-indianapolis

Biggest LBO Ever, SPAC 2.0, Open Source AI Models, State AI Regulation Frenzy

(0:00) Chamath and Jason welcome Rep. Ro Khanna!
 
(1:10) H-1Bs and immigration
 
(8:40) Giving Trump credit as a Progressive Democrat, why bipartisanship is broken, future Democratic leaders
 
(15:08) Tech industry: Can Democrats win back tech?; Economic patriotism, protection vs proliferation of AI
 
(24:25) Government shutdown, what actually happens?
 
(30:25) Extreme rhetoric: Importance of dialing this down
 
(36:29) Censorship and lawfare on both sides
 
(40:32) Crime issues in major cities, why Democrats are losing on safety, common sense solutions
 
(47:46) Mamdani's surge: is Zohran the future of the party?
 
(51:15) Congressional stock trading ban
 
Follow Ro Khanna:
 
https://x.com/rokhanna
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg
 
Intro Video Credit:
 
https://x.com/TheZachEffect

Ro Khanna on Crime, Censorship & Congress: Fixing What’s Broken in America

(0:00) Introducing Kyle Samani
 
(1:07) History of modern capital markets
 
(3:25) What a redesigned capital market structure would look like in 2025
 
(8:22) Examples of the future of internet capital markets
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket - https://www.polymarket.com/
 
Follow Kyle:
 
https://x.com/KyleSamani
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Multicoin Capital’s Kyle Samani on Internet Capital Markets

(0:00) Introducing Rick Caruso
 
(1:03) Reflecting on the disastrous LA Wildfires: Karen Bass failure, saving the Palisades Village, failure to rebuild
 
(11:20) California’s incompetence, running for CA Governor vs LA Mayor
 
(14:21) Attention to detail
 
(17:04) State of California: What it should be, homelessness, National Guard, policing
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket - https://www.polymarket.com/
 
Follow Rick Caruso:
 
https://x.com/RickCarusoLA
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Rick Caruso on California’s Collapse: Broken Leadership, LA Wildfire Failures & the Fix

(0:00) Introducing Arm CEO Rene Haas
 
(1:08) Lessons from working with Jensen Huang
 
(3:20) Arm’s history, understanding Nvidia’s dominance in AI, training vs inference, physical AI market size
 
(10:01) China’s AI ecosystem, the US-Intel deal, rare earths, creating a US “national champion”
 
(15:35) Manufacturing in America: how to create a culture of excellence?
 
(18:34) US export controls, building in the UK
 
(23:42) US-China AI arms race
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket: https://www.polymarket.com
 
Follow Rene: https://x.com/renehaas237
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Arm CEO Rene Haas on AI: Nvidia Lessons, Intel’s Decline and the US-China Chip War

(0:00) Introducing Cleo Abram
 
(1:12) Why YouTube has become the best platform for creators, techno-optimism at Huge If True
 
(8:35) Astrophysicist Alex Filippenko on the James Webb Space Telescope
 
(23:14) Q&A with Alex Filippenko, Cleo, and Friedberg: The universe, Fermi Paradox, black holes, NIH grants and the “war on science”
 
(37:37) Zipline CEO Keller Rinaudo Cliffton on the future of drone delivery
 
(53:29) Q&A with Keller Rinaudo Cliffton, Cleo, and Friedberg: Instant delivery explosion, competitors, impact on healthcare
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket - https://www.polymarket.com/
 
Follow Cleo:
 
https://x.com/cleoabram
 
https://www.youtube.com/c/CleoAbram
 
Follow Keller:
 
https://x.com/keller
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Science Corner Special: David Friedberg, Cleo Abram, Alex Filippenko, and Keller Rinaudo Cliffton

(0:00) Introducing Eli Lilly CEO Dave Ricks
 
(1:43) How Eli Lilly discovered the GLP-1 impact on weight loss, counterfeit products from China
 
(7:08) GLP-1 pricing and capital allocation after a breakout pharma product
 
(12:56) Why Biotech VC has plummeted, “patent hacking” in China
 
(15:32) Dave’s health regimen: good sleep, movement, healthy diet, social relationships, reading
 
(18:32) Unexpected impacts of GLP-1s, helping with addictions, potential mental health use cases
 
(21:16) Thoughts on RFK Jr, Big Pharma’s influence on the media, how AI empowers patients
 
(25:27) Impact of proposed NIH cuts, explaining the “PBM boogeyman”, next major pharma breakthrough
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket: https://www.polymarket.com/
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Inside the GLP-1 Gold Rush: Eli Lilly CEO on New Breakthroughs, Addiction & Mental Health, Pricing

(0:00) Bestie intros!
 
(2:23) H-1B overhaul: origins and exploitation
 
(25:26) Autism linked to Tylenol usage during pregnancy
 
(43:42) Jimmy Kimmel returns to ABC: comments and reactions
 
(59:21) Two major AI papers
 
(1:09:00) YouTube update
 
(1:12:53) Alphabet admits to COVID censorship under Biden, new CA online hate speech law
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg
 
Intro Video Credit:
 
https://x.com/TheZachEffect
 
Referenced in the show:
 
 https://polymarket.com/event/will-courts-block-trumps-100k-h1b-by-september-30
 
 https://www.cnbc.com/2015/08/18/trump-sort-of-right-on-silicon-valley-visas-calacanis.html
 
https://x.com/RobertMSterling/status/1873174358535110953
 
 https://www.firstpost.com/explainers/deepseek-employees-travel-ban-china-13872040.html
 
 https://www.axios.com/2019/12/29/trump-att-outsourcing-h1b-visa-foreign-workers
 
 https://hub.jhu.edu/2019/11/05/acetaminophen-pregnancy-autism-adhd/
 
https://x.com/ThaaatColin/status/1958690862185230539
 
https://x.com/ThaaatColin/status/1958690862185230539
 
 https://polymarket.com/event/jimmy-kimmel-out-by-september-30?tid=1758935046582
 
https://x.com/sahilkapur/status/1970211641124847711
 
https://x.com/shawn_farash/status/1971289990283002022
 
https://x.com/Scott_Wiener/status/1970307297999007773
 
https://x.com/thackerpd/status/1971246303243010172
 
https://support.google.com/youtube/answer/7354993?hl=en
 
 https://judiciary.house.gov/media/press-releases/google-admits-censorship-under-biden-promises-end-bans-youtube-accounts
 
https://arxiv.org/pdf/2509.13351
 
https://www.nature.com/articles/s43588-025-00854-1#Abs1

H-1B Shakeup, Kimmel Apology, Autism Causes, California Hate Speech Law

(0:00) Introducing Eric Schmidt
 
(1:59) Thoughts on remote work and work-life balance
 
(3:49) Approaching AI: US vs China
 
(8:04) Relativity Space, rockets, drones, defense, and more
 
(17:32) Future role of America, and the decline of the West
 
(21:51) AGI: boom or bust?
 
Thanks to our partners for making this happen!
 
Solana - Solana is the high performance network powering internet capital markets, payments, and crypto applications. Connect with investors, crypto founders, and entrepreneurs at Solana’s global flagship event during Abu Dhabi Finance Week & F1: https://solana.com/breakpoint
 
OKX - The new way to build your crypto portfolio and use it in daily life. We call it the new money app. https://www.okx.com/
 
Google Cloud - The next generation of unicorns is building on Google Cloud's industry-leading, fully integrated AI stack: infrastructure, platform, models, agents, and data. https://cloud.google.com/
 
IREN - IREN AI Cloud, powered by NVIDIA GPUs, provides the scale, performance, and reliability to accelerate your AI journey. https://iren.com/
 
Oracle - Step into the future of enterprise productivity at Oracle AI Experience Live. https://www.oracle.com/artificial-intelligence/data-ai-events/
 
Circle - The America-based company behind USDC — a fully-reserved, enterprise-grade stablecoin at the core of the emerging internet financial system. https://www.circle.com/
 
BVNK - Building stablecoin-powered financial infrastructure that helps businesses send, store, and spend value instantly, anywhere in the world. https://www.bvnk.com/
 
Polymarket: https://www.polymarket.com/
 
Follow Eric:
 
https://x.com/ericschmidt
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg

Eric Schmidt on AI, the Battle with China, and the Future of America

(0:00) Reacting to Charlie Kirk's death: impact, legacy, and what's wrong in America
 
(15:27) Assassination culture in America, online radicalization
 
(30:37) Jimmy Kimmel suspended indefinitely by ABC
 
(49:11) The Ellison Media Empire: Paramount, Warner Bros Discovery, TikTok
 
(1:01:09) Besties discover their recent YouTube videos have been flagged as "Restricted"
 
(1:06:23) All-In Summit recap
 
Follow the besties:
 
https://x.com/chamath
 
https://x.com/Jason
 
https://x.com/DavidSacks
 
https://x.com/friedberg
 
Follow on X:
 
https://x.com/theallinpod
 
Follow on Instagram:
 
https://www.instagram.com/theallinpod
 
Follow on TikTok:
 
https://www.tiktok.com/@theallinpod
 
Follow on LinkedIn:
 
https://www.linkedin.com/company/allinpod
 
Intro Music Credit:
 
https://rb.gy/tppkzl
 
https://x.com/yung_spielburg
 
Intro Video Credit:
 
https://x.com/TheZachEffect
 
Referenced in the show:
 
https://x.com/charliekirk11/status/1909391943802703899
 
https://www.bbc.com/news/articles/c99g1e0z2ero
 
 https://networkcontagion.us/reports/4-7-25-ncri-assassination-culture-brief
 
 https://www.rollingstone.com/politics/politics-features/randi-weingarten-excerpt-fascists-hate-critical-thinking-1235428379
 
 https://www.theguardian.com/us-news/2017/aug/18/new-yorker-and-economist-covers-slam-trumps-defence-of-white-supremacists
 
https://x.com/jk_rowling/status/1966256971134234678
 
https://x.com/megynkelly/status/1968477822982480298
 
https://x.com/LizMacDonaldFOX/status/1968837993797665085
 
 https://www.nexstar.tv/nexstar-abc-affiliates-to-preempt-jimmy-kimmel-live-indefinitely-beginning-tonight
 
https://x.com/bennyjohnson/status/1968359685045838041
 
https://x.com/TheChiefNerd/status/1968492589201396052
 
 https://www.nbcnews.com/pop-culture/tv/jon-stewart-rips-paramount-cbs-diatribe-cancellation-colbert-late-show-rcna220144
 
 https://latenighter.com/features/analyst-network-late-night-talk-shows-became-unprofitable-in-2023
 
https://x.com/stoolpresidente/status/1968474692886340002
 
 https://variety.com/2025/tv/news/paramount-warner-bros-discovery-acquisition-consolidation-analysis-1236515947
 
 https://www.wsj.com/tech/details-emerge-on-u-s-china-tiktok-deal-594e009f
 
 https://polymarket.com/event/who-will-acquire-tiktok-559?tid=1758241123068
 
https://arxiv.org/pdf/2209.07663

Charlie Kirk Murder, Assassination Culture in America, Jimmy Kimmel Suspended, Ellison Media Empire

Follow @chamath: https://twitter.com/chamath
 
Follow @jason: https://twitter.com/Jason
 
https://linktr.ee/calacanis
 
0:01 Jason checks in on Chamath, Sacks & Friedberg, opening up their social circles, outdoor activities & more
 
9:31 Issues with politicizing matters of public health, deaths decreasing while new cases spike, masks, lockdowns & more
 

 20:56 Viral videos, doxxing bad behavior & cancel culture
 

 25:39 Reforming law enforcement, separating police from the military, changing police incentives
 

 36:42 Are public unions too powerful? How a lack of leadership has led us here
 

 41:49 Facebook vs. Twitter on free speech, Zuckerberg's relationship with Peter Thiel, valuing comfort over freedom of expression
 

 59:24 John Bolton's book controversy
 

 1:03:14 Movements in the COVID vaccine space
 

 1:07:38 Trump vs. Biden: Who has the upper hand?
 

 1:14:24 Who should Biden pick as VP?

E4: Politicizing the pandemic, Police reform, Biden's ideal VP, Twitter vs. Facebook on free speech & more with David Sacks & David Friedberg

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