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Global

Award-winning LBC presenter and best-selling author James O’Brien hosts a series of compelling conversations with fascinating people from the worlds of politics, news and entertainment. These are thoughtful conversations with a curious and interested interviewer.

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Full Disclosure with James O'Brien

Growing up in Bristol, acclaimed playwright and screenwriter Jack Thorne was a shy, politically driven kid who believed he could change the world- first through politics, then acting, before discovering that storytelling was where his voice truly belonged.

In this episode of Full Disclosure, James O’Brien sits down with the Emmy and BAFTA-winning creator of This Is England, His Dark Materials, Harry Potter And The Cursed Child and Adolescence to trace Jack’s journey from a lonely teenager to one of the most prolific writers of his generation. They talk about ambition, failure, neurodiversity, and the years of illness that left Jack literally allergic to movement, and how that experience shaped his empathy, activism and craft.

This conversation reveals a writer driven not by fame, but by purpose- to make television and theatre more inclusive, more truthful, and more alive to the lives of those too often left out of the story.

Find out more about television series The Hack here

Jack Thorne: “I was allergic to moving - the doctor said, ‘This might be forever.’”

In 2013, businesswoman and mum Cor Hutton was given just a five percent chance of survival after contracting pneumonia that developed into sepsis. She pulled through, but lost both hands and her legs below the knee.

In this episode of Full Disclosure, James O’Brien speaks to Cor about her extraordinary journey- from relearning how to live as a quadruple amputee to becoming the first person in Scotland to receive a double hand transplant. They discuss her founding of the charity Finding Your Feet, the physical and emotional resilience behind her recovery, and the mountains- literal and metaphorical- she has climbed since.

Powerful, moving and often laced with humour, this conversation reveals Cor not just as a survivor, but as a campaigner, mother and relentless optimist- someone who proves that lives can be rebuilt and transformed, no matter how impossible the odds.

Right now, too many people are facing their toughest challenges - alone. Families living with life-limiting illness. People struggling with their mental health. Those trapped in abuse or unable to afford the basics. They need help. And they need it now. At Global’s Make Some Noise, we’re funding vital projects in communities right across the UK, small charities working on the front line of these challenges - but we can’t do it without you. Every day without funding means someone goes without support. Your donation could mean a safe place to turn, a vital phone call answered, a life changed. Help us to make sure no one faces life’s toughest challenges alone. 

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Cor Hutton: The Quadruple Amputee Who Found Her Feet

Before he became one of the world’s best-known chefs, Jamie Oliver was a dyslexic kid growing up in his parents’ pub in rural Essex, learning the value of hard work, fresh food, and family.

In this episode of Full Disclosure, James O’Brien sits down with Jamie to trace his journey from peeling veg at his parents’ pub to fronting The Naked Chef, reshaping school dinners, and building - then losing - a restaurant empire. They talk about the resilience required to recover from failure, his uncompromising campaigns on child health, and why he still feels driven to “stir the pot” when government policy falls short.

Candid, emotional and often surprising, this conversation goes beyond the celebrity image to reveal Jamie as a father, activist and creative obsessive- a man who sees food not just as sustenance, but as a way to change lives.

Find out more about Jamie Oliver’s Eat Yourself Healthy here

Jamie Oliver: “I’d gone from being skint to having a lot of money, I felt like a fake.”

Before becoming Ireland’s youngest Taoiseach, Leo Varadkar was a Dublin GP with bold ambitions and a belief that politics could be a kind of medicine for society.

In this episode of Full Disclosure, James O’Brien sits down with the former Prime Minister to explore his extraordinary rise from a mixed-heritage childhood in 1980s Ireland, to leading his country through Brexit battles, historic referendums and the turbulence of the pandemic. They discuss the unlikely path that took him from medical practice to the world stage, the emotional costs of leadership, and why he chose to step away at just 45 years old.

Frank, reflective and often surprising, this is a conversation about resilience, identity, and what it really means to hold power in a changing Ireland

Find out more about Leo Varadkar’s memoir Speaking My Mind here

Leo Varadkar: Former Prime Minister of Ireland on Power and Letting Go

Britain’s leading forensic pathologist Dr Richard Shepherd has performed over 23,000 postmortems and given evidence in some of the most high-profile cases of our time, from Hungerford to Hillsborough, from Princess Diana to David Kelly. But his fascination with death began much earlier, when his mother died suddenly from heart disease and he was left with questions no one could answer.

In this episode of Full Disclosure, Dr Shepherd tells James O’Brien how that childhood loss set him on the path to forensic medicine, how his father’s emotional openness shaped him, and how a book brought into school by a friend gave him his first glimpse of a profession that would define his life. He reflects on the leap from observing to performing autopsies, the responsibility of telling the truth in court, and the lasting emotional toll of cases that never leave you.

Candid, unflinching and deeply human, Dr Shepherd shares how a lifetime spent uncovering the truth about death has shaped the way he lives.

Find out more about Dr Richard Shepherd Time of Death tour here

Dr Richard Shepherd: Lessons from 23,000 Postmortems- including Hungerford, Hillsborough and Princess Diana

Actor, comedian and bestselling author Arabella Weir grew up in a family that prized intellect and appearances but struggled to offer love. In this episode of Full Disclosure, she tells James O’Brien how an unsettled childhood shaped her fearless streak, her need to perform, and her instinct to turn pain into comedy.

From the brutal remarks of her mother to the liberating chaos of Camden School for Girls, Arabella charts the path that took her from rejection at drama schools to finding her voice on The Fast Show and beyond. She reflects on the role of therapy, the challenge of writing, and what it means to live alongside the little girl she once was.

Wry, fearless and full of heart, Arabella shares how survival became strength- and why she’s determined to live on her own terms.

Find out more about An Evening with The Fast Show here

Arabella Weir: At nine my mum said, “I can’t bear the sight of you”

Natalie Haynes has never been easy to categorise. A stand-up comedian turned broadcaster and best-selling author, she has built a career out of making the ancient world vivid, funny and urgent. In this episode of Full Disclosure, James O’Brien talks with the presenter of Stand Up for the Classics about her unusual path from Birmingham bookshops to the Edinburgh Fringe, and from Radio 4 to re-imagining Medea.

They explore the strange alchemy of combining scholarship with humour, the myths that refuse to let her go, and why Jason may be one of antiquity’s least heroic heroes. Natalie reflects on the teachers and family who first filled her life with books, the risks of carving out a career that no one else was doing, and the joy of turning classical stories into something alive for modern audiences.

Clever, warm and very funny, Natalie shows how ancient tragedy and modern comedy can illuminate each other- and why she still feels most at home with the ghosts of Greece.

Find out more about Natalie Haynes book and tour No Friend to This House here

Natalie Haynes: Greek Myths, Medea and the Comedy of Classics

From a childhood in Dundee marked by loss, poverty and resilience, to becoming one of the most respected actors of his generation, Brian Cox’s life and career have been defined by an unrelenting pursuit of truth on and off stage. In this in-depth conversation with James O’Brien, the Emmy and Golden Globe winner reflects on the death of his father at eight years old, the formative influence of his mother’s struggles with mental health, and the teachers who first spotted his talent.

Cox charts his journey from the Dundee Repertory Theatre to the Royal Shakespeare Company, the West End and Hollywood, revisiting the defining roles that shaped his craft- from portraying Hannibal Lecter before Anthony Hopkins to his acclaimed turn as Logan Roy in Succession. He speaks candidly about the compromises and convictions that have steered his career, the cultural and political forces that have shaped his worldview, and his ongoing belief in the power of storytelling to confront injustice.

Thoughtful, uncompromising and rich with anecdote, this episode offers a compelling portrait of an actor whose commanding presence is matched by his fierce intellect and refusal to play by the rules.

From The Vault: Brian Cox

From a childhood in Oxford shaped by unconditional love, Jewish heritage and a keen sense of curiosity, to a career spanning stage, screen, voice work and bestselling memoir, Miriam Margolyes’ life has been anything but ordinary. In this candid conversation with James O’Brien, the beloved actor reflects on the security of her early years, the sting of antisemitism, and the moment she first felt at home on stage. She recalls her path from Cambridge Footlights to the BBC, the breakthrough of her one-woman show Dickens’ Women, and the global recognition that came with Harry Potter.

Margolyes speaks openly about her voracious appetite for people and stories, her refusal to shy away from controversy, and the enduring influence of her parents- from her mother’s theatrical aspirations to her father’s financial frankness. Along the way, she shares unvarnished memories of working with Hollywood greats, the exhilaration of live performance, and the friendships collected across decades in the public eye.

Frank, funny and utterly herself, this episode offers an unfiltered portrait of a national treasure who remains as curious, mischievous and compelling as ever.

From The Vault: Miriam Margolyes

Cariad Lloyd never set out to become the voice of modern grief, but after losing her father at just fifteen, the silence around death stayed with her. In this episode of Full Disclosure, James O’Brien speaks with the actor, comedian and creator of Griefcast podcast about how turning her personal loss into public conversation has transformed both her life and others'.

Together they explore the tension between comedy and sorrow, the strange rituals of mourning, and why so many of us feel unequipped to talk about death. Cariad shares the moments that shaped her, the people she’s never forgotten, and how the making of her book You Are Not Alone helped her say what so many struggle to find words for.

Poignant, funny, and gently radical, Cariad reflects on love, loss, and learning to hold space for the chaos of being human.

Find out more about Cariad Lloyd’s children’s book, Where Did She Go?: A heartfelt story to help children understand loss here

Cariad Lloyd: Talking About Grief Changed My Life

One of the UK's best loved comedians Russell Howard joins James this week. They discuss Russell's rise to fame. 
From Stand-Up at the age of 18, to the encouragement of his parents for him to pursue comedy full time, and how Mock the Week became the turning point in his career. 

Full Disclosure is an in depth interview series chatting to the world's most fascinating people, hosted by James O'Brien.

Rate and subscribe on Global Player or wherever you get your podcasts and connect with James on Twitter: @mrjamesob

Russell Howard

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