TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity

TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity

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In this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments.

You'll learn:

• Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit. • Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone. • How erectile dysfunction is a sensitive marker of overall health and heart risk. • The efficacy of Cialis/Viagra for both erections and cardiac protection, and the risks of unchecked influencer advice on steroids. • The direct link between muscle mass, exercise, and sexual function—and why the penis is the "first to go" when overall health declines.

Chapter Markers:

0:00 - Testosterone is a Brain Hormone

0:40 - Debunking the Myth: Male Menopause (Andropause) Doesn't Exist

1:33 - The Dangers of Unchecked Influencer Advice on Testosterone

3:07 - Defining Testosterone Deficiency: Symptoms vs. Signs

5:10 - The Arbitrary Number: Why Guidelines Disagree on Low T

8:29 - Free Testosterone: The Most Reliable Indicator of Male Health

15:28 - TRT vs. Steroids: Defining the Line and Risks

18:59 - The Real Risks of TRT: Infertility and Hematocrit

22:36 - The Shocking Backstory: Challenging the Prostate Cancer Myth

26:40 - Erectile Dysfunction (ED) and Lifestyle Modification

29:21 - Shockwave Therapy for ED: The Science and the Cash Business

33:53 - Penile Tissue Atrophy and Venous Leak

37:25 - The Role of Muscle Mass, Sarcopenia, and Sexual Function

39:41 - The Single Best Marker for Male Health: Erectile Function

42:02 - The Science of Cialis and Viagra (PDE5 Inhibitors)

45:49 - The Viagra Story: From Heart Drug to ED Cure

50:50 - Tadalafil (Cialis) as a Triple-Threat Drug (Cardiac, Urinary, Sexual)

53:57 - The Role of Testosterone in Female Sexual Function

55:20 - Hypogonadism: Diagnosis, Treatment, and Fertility Risk

About the guests:

Dr. Abraham Morgentaler is an Associate Clinical Professor of Urology at Harvard Medical School and founder of Men's Health Boston. He is an internationally recognized expert in men's health, particularly known for his pioneering work in testosterone therapy. Dr. Morgentaler is credited with reversing the long-held belief that testosterone therapy causes prostate cancer and is the author of several books on men's health.

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Dr. Tobias Kohler is the co-founder of the Erectile Restoration Outcomes Study (EROS) penile implant registry. In addition to his clinical and research activities, Dr. Kohler is active in education, providing mentorship to residents and fellows.

Mayo Clinic ResearchGateLinkedIn


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