It begins when hardheaded mountain matriarch Granny Mustard decides she wants to live forever, but is killed before she can achieve her goal. Her slow-witted but equally hardheaded granddaughter Jenkie decides to pick up the ball and run with it. She takes Granny’s unperfected immortality moonshine recipe, a socially-inept friend named Bink, and dreams of fame and fortune to an abandoned trailer up in Desper Hollow. But slow-witted can’t stand against the terrible power Granny initiated. Jenkie’s experiments worsen the troubles with Granny’s original recipe. Now, it brings dead critters and a few stray dead folks back to a state of hungry, vicious, mindless animation. Now a stash of the living dead is locked up in the back of the Jenkie’s trailer, a howling herd that has Jenkie terrified. And Armistead, one of the red-eyed living dead, seems way too alert for comfort… .