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BBC World Service


The BBC brings you all the week's science news.


Science In Action

Over the last week, news of “synthetic human embryos” has made headlines around the world. Science in Action is getting to the bottom of the sensational story. 

We talk to two of the researchers who have made the embryo models from stem cells in their labs; Professor Magdalena Zernicka-Goetz from the University of Cambridge and California Institute of Technology, and Professor Jacob Hanna from the Weizmann Institute of Science in Israel. They tell us how they made the embryo models, what their aims are, and their own ethical considerations. 

The scientific community is excited, but not surprised, by the breaking research. We hear how Dr Andreia Bernardo, group leader at Imperial College London, could use these structures in her future research. 

Finally, Director of the Reproductive Sociology Research Group at Cambridge University, Professor Sarah Franklin, and Professor of Law at Stanford University, Hank Greely, tackle the legal and ethical constraints on this kind of work, and why it is important for understanding the health of mothers and babies. 

Photo Credit: Magdalena Zernicka-Goetz Lab

Presenter: Roland Pease 
Producer: Ella Hubber

Human embryo models

Heatwaves in the pacific ocean have had a devastating effect on seabird populations in the north eastern US. Julia Parrish and colleagues publish this week 4 million deaths of Alaskan common murres attributable to rising water temperatures during 2014-16, representing half the population. One idea is that the fish on which the birds feed swim at deeper depths to find cooler temperatures, taking them below the depth the birds can dive. Worse, the reduced population numbers have endured almost ten years later. 

Pre-eclampsia affects up to 5 percent of pregnancies across the world. It reduces blood flow through the placenta, endangering mother, and even hindering the development of the foetus. But a promising approach to a possible therapy is described by Kelsey Swingle and colleagues this week. Much like some covid vaccines, by using a sort of lipid nanoparticles to deliver mRNA directly to the placenta in pregnant mice has resulted in healthier outcomes by widening the placental capillaries, allowing blood to flow more normally.

Angie Rasmussen updates Roland on some of the work reported at a conference in Japan this week, pointing more directly to the covid-19 pandemic originating from wild animals at the Wuhan market.

And in two coordinated papers published in the journals Science and Nature this week, scientists have narrowed down the period of time in history that modern humans and neanderthals interbred, leading to nearly everyone outside of sub-Saharan Africa sharing up to 2% of European Neanderthal DNA today. The question remains as to whether it was a benefit or not to the resulting hybrid population. Co-author Manjusha Chintalapati and colleagues describe how not all the neanderthal crossovers went on to survive pre-history to count as our direct ancestors. But one period of time, around 47,000 years ago is stamped on (nearly) all of us.

Presenter: Roland Pease
Producer: Alex Mansfield
Production Coordinator: Jana Bennett-Holesworth and Josie Hardy

(Image: Group of common murres on a breeding colony in Alaska. Credit: Sarah Schoen/USGS)

Warming oceans kill millions of birds

New insights into how our skin learns to tolerate and co-exist with bacteria on its surface show great potential for the development of simpler and less invasive vaccines. Stanford University’s Djenet Bousbaine has published two papers in Nature detailing the microbiological research and mouse vaccination experiments that could change the future of immunisation.
 
The Sun is the hardest place in the Solar System to reach. But by the time the next edition of Science in Action is on air, NASA’s Parker Solar Probe will have swooped through the scorching corona layer of the Sun, re-emerged, and be readying itself to relay the details of magnetic fields and particle storms to the team. NASA Helioscience deputy manager, Nicky Rayl, reveals all about the mission and explains why the Parker Probe’s future looks bright.
 
And a trip half a billion years back - and then some - to the dawn of complex life here on Earth. Microfossil hunter Shuhai Xiao, from Virginia Polytechnic Institute and State University, has been compiling a single statistical database to better understand evolution during the so-called ‘boring billion’, why subsequent changes on the planet triggered a new diversity of species to emerge, and how the interplay between biology and geology has paved the way for modern life as we know it.

Presenter: Roland Pease
Producer: Alex Mansfield
Assistant Producer: William Hornbrook
Production Coordinator: Jana Bennett-Holesworth

(Image: Solar Activity Captured in H-Alpha Filter. Credit: Manuel Romano/NurPhoto via Getty Images.)

Sun Grazing

Sars CoV-2 has been with us for five years. In the first of a two-part special, Science in Action asks how well was science prepared for it? And are we any better prepared for the next one?

Presenter: Roland Pease
Producer: Alex Mansfield, with Debbie Kilbride
Production co-ordinator: Jana Bennett-Holesworth

Five years of Covid: Part one

Sars CoV-2 has been with us for five years. In the second of a 2-part special, Science in Action asks how well was science prepared for it? And are we any better prepared for the next one? 

Presenter: Roland Pease 
Producer: Alex Mansfield, with Debbie Kilbride 
Production Coordinator: Jana Bennett-Holesworth

Five years of Covid: Part two

H5N1 bird flu is still spreading across farms in the USA and this week claimed its first human life in North America - an elderly patient in Louisiana infected by backyard poultry. But last week, Sonja Olsen, Associate Director for Preparedness and Response in the CDC’s flu division, and her colleague Shikha Garg, published new analysis in the New England Journal of Medicine summarizing the human cases and epidemiology so far. 

A lab study underscoring a suspected link between the virus responsible for cold sores, and Alzheimers, the most common form of dementia, has been published in Science Signalling this week. The study, by Dana Cairns of Tufts University, looks at whether repetitive brain trauma – another risk factor - adds to the evidence that latent herpes simplex can be involved. 

Song Lin, a chemist at Cornell University who has won prizes for pioneering the use of electrical currents to drive chemical reactions rather than heat, has teamed up with Cornell micro engineer Paul McEuen to power up a new kind of chemistry and invent another kind of SPECS – an acronym for Small Photoelectronics for Electrochemical Synthesis. They outlined their first generation device and the promises it brings in Nature this week.

Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Jana Bennett-Holesworth

(Photo: Chickens eating feed. Credit: San Francisco Chronicle/Getty Images)

First US avian flu fatality

New types of snake-bite anti-venoms are designed by AI. Also, how much meat did human ancestors eat? How the Baltic Nord Stream gas pipeline rupture of 2022 was the biggest single release of methane ever caused by humans, and that Pluto met Charon, not with a bang, but more of a kiss.

Using a high precision technique for spotting different isotopes of Nitrogen, Tina Lüdecke of the Max Planck Institute for Chemistry has concluded that a group of early hominin Australopithecus living in South Africa were predominantly vegetarian, putting the date that human ancestors started eating meat (and thence growing bigger brains) to more recently. The technique, she thinks, can enlighten prehistoric food webs and ecologies from millions of years ago.

Last year’s Nobel prizes showed the potential new techniques of AI to design synthetic proteins. Timothy P Jenkins and colleagues decided to try designing treatments for snakebite venoms, with remarkable apparent success. It could save many thousands of lives a year.

Since the September 2022 explosions at the Nord Stream gas pipeline in the Baltic sea, many different analyses of how much methane was released have provided a variety of estimates. This week, scientists at the UNEP International Methane emissions observatory – including Stephen Harris - published a study estimating it to be a little under half a million tonnes, making it by far the single biggest human caused release of this most dangerous greenhouse gas. Yet, they say, even that is a tiny fraction of what is released overall around the world every year. 

And Finally, a new analysis of the original formation of the Pluto-Charon binary Dwarf Planetary system suggests they – and possibly many other Kuiper belt pairing – were born of a gentle astronomical dance and a peck on the cheek, rather than the catastrophic collision we associate with the earth-moon’s fiery first date. And it may have lasted just a matter of days, according to author Adeene Denton of the University of Arizona.

Presenter: Roland Pease
Producer: Alex Mansfield
Production Coordinator: Jana Bennett-Holesworth

(Photo: Gorilla feeding. Credit: WLDavies/Getty Images)

AI antivenoms and vegetarian hominids

Thirty per cent of the Arctic is switching from carbon sink to carbon source. But could future fertilizer be made deep underground using less resources? Also, how and perhaps why globally 2024 had the highest number of fatal landslides in over 20 years, and an unexpected sound from space prompts a re-evaluation of how the earth’s magnetic field interacts with the environment around it.

Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Jana Bennett-Holesworth

(Photo: Magnificent icebergs. Credit: MB Photography/Getty Images)

Arctic carbon starting to flip

Nasa's OSIRIS-REx mission to collect a sample from an asteroid has been a great success. Asteroid Bennu's sample yields a watery pool of history, thanks to an international team of scientists including the London Natural History Museum's Sarah Russell. 

Also, in a week of tumultuous changes to federal funding and programmes, we hear from some US scientists affected and concerned by Executive Orders from the White House. Betsy Southwood, formerly of the Environmental Protection Agency, is worried not just about the government employees’ careers, but the environment itself and the whole of environmental science in the US and the world. Chrystal Starbird runs a lab at the University of North Carolina and is worried about the fate of grants aimed at diversifying scientific expertise, but also that some grant schemes are getting erroneously included in the anti-DEI clampdown. And Lawrence Gostin is an eminent health lawyer, proud of the NIH and all it has achieved.

Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Jana Bennett-Holesworth

(Photo: OSIRIS-REx Sample Return. Credit: Nasa/Getty Images)

Make science great again

The mystery swarm of small earthquakes near the island of Santorini beg for more data collection. Also, the National Oceanic and Atmospheric Administration (NOAA) in the US goes offline and whales learn song like kids learn language.

Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Josie Hardy

(Photo: Greece earthquake. Credit: AFP)

Earthquakes swarms and whale chart toppers

A computer processor made of carbon nanotubes is unveiled to the world. Also, the continuing quest for nuclear fusion energy, and the stats on crocodile attacks since the 1960s.

(The world's first 16 bit microprocessor made of carbon nanotubes. Credit: Max Shulaker)

Nanotube computer says hello

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