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The Big Take from Bloomberg News brings you inside what’s shaping the world's economies with the smartest and most informed business reporters around the world. The context you need on the stories that can move markets. Every afternoon.


Big Take

Treating cancer is a massive business. In 2024 alone, cancer treatments generated at least $200 billion in worldwide sales for the pharmaceutical industry, more than the obesity drug rush. But a Bloomberg News analysis showed that fewer than half of treatments reviewed — some of which have painful side effects — have been shown to extend patients’ lives.
 
On today’s Big Take podcast, Bloomberg senior healthcare reporter Robert Langreth takes host David Gura inside what some doctors call the “cancer-industrial complex” — from the regulatory landscape that ushered in a wave of lucrative new drugs to the damaging financial and health impacts some treatments can have on patients.
 
Read more:
 
Cancer Drugs Cost More Than Ever. They Often Don’t Extend Lives.
 
The Implants Were Supposed to Dissolve. They Didn’t.
 
Pharma Is Pushing $200,000 Cancer Drugs When Cheaper Doses May Work
 
Cancer Doctors Are Making a Fortune Off Drug-Trial Participants
 
One Generic Cancer Drug Costs $35. Or $134. Or $13,000.

See omnystudio.com/listener for privacy information.

Many Cancer Drugs Don’t Extend Life

The Philippines is no stranger to typhoons, but this year’s storms exposed something far uglier: a vast corruption scandal.
 
On today’s Big Take Asia Podcast, host K. Oanh Ha speaks to Bloomberg’s Andreo Calonzo and Rosalind Mathieson about how billions of dollars earmarked for flood control vanished and what the crisis means for the country’s political and economic stability.

See omnystudio.com/listener for privacy information.

The $2 Billion Flood Control Scandal Rocking the Philippines

All year, the jobs market, consumer sentiment, AI and inflation flashed warning signs about the economy — but 2025 managed to avoid a recession.
 
On today’s Big Take podcast, host Sarah Holder talks with Bloomberg’s Stacey Vanek Smith and Moody’s Analytics Mark Zandi to understand what this year’s wonky economy can tell us as we head into 2026 and what to watch for in the new year.
 
Read more: US Recession Risk Is Receding as We Move Into 2026

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Wait, Weren’t We Supposed to Have a Recession in 2025?

Mustafa Suleyman co-founded AI lab DeepMind when he was just 26 years old. Four years later, it was acquired by Google for a reported $400 million. 

He is now head of Microsoft’s AI unit, where he just unveiled a new superintelligence team tasked with creating an AI that can outperform humans at all tasks.

In this conversation with Mishal Husain, Suleyman talks about the decisions society has to make about AI, the white-hot war over tech talent and the competition with other tech bros. 
 
00:00 - Introduction from Mishal Husain
02:20 - Suleyman’s daily use of AI
04:52 - Stoicism and the magic of AI
05:50 - Defining superintelligence
07:35 - The AI Wild West
09:20 - Humans misusing technology
11:43 - Promise of abundance, universal basic income
14:30 - Suleyman’s family and decision to drop out of Oxford
19:37 - "Decisions we make may have very lasting consequences”
21:04 - Exploring the ‘broligarchy’
22:28 - His view of Sam Altman and Open AI
24:11 - Conversations with Demis Hassabis about Gemini 3
26:15 - “I’m sort of a centrist these days”
28:09 - AI containment and the role of government 
29:58 - Microsoft’s revised deal with OpenAI: “It is a shift for us”
31:42 -The talent war and ‘Zuck’s’ pay packages
34:12 - Circular deals in AI: “Watching it carefully”
36:22 - “I really want to nail medical superintelligence”
37:36 - Suleyman on using AI for emotional support
40:21 - The UK lacks the “hustle culture” of Silicon Valley
42:13 - AI news reporters: “We’re exploring everything”
 
Watch this podcast here: https://www.youtube.com/playlist?list=PLe4PRejZgr0Ns_wjGlmjlPz0cded0nTYS
 
You can find the written version of this interview with Mishal’s notes on Bloomberg Weekend: https://www.bloomberg.com/latest/weekend-interview
 
Contact The Mishal Husain Show mishalshow@bloomberg.net
 
Subscribe today on Apple Podcasts and Spotify.

See omnystudio.com/listener for privacy information.

Weekend Listen: The Man Driving Microsoft’s New AI Strategy

Depending on who you talk to, AI is the key to remaking industries and jobs – or a bubble ripe to pop. And if you’re an investor, you’re already exposed.
 
So what’s the best strategy for investing in AI now? On today’s Big Take podcast, host Sarah Holder and Bloomberg personal finance reporter Suzanne Woolley talk to experts – ARK Invest’s Cathie Wood, Fidelity International’s Taosha Wang, Allspring Global Investments’ Michael Smith and Janus Henderson Investors’ Denny Fish – about coming AI investment waves and potential warning signs. 

See omnystudio.com/listener for privacy information.

How to Invest in AI Right Now

From rising costs to shifting markets, American farmers are struggling to make ends meet. Now, the White House is stepping in.
 
On today’s Big Take podcast, David Gura sits down with Bloomberg agriculture Reporter Erin Ailworth and a fifth-generation farmer to discuss President Trump’s $12 billion farm aid plan. What prompted the move, which sectors will be eligible and how ongoing tensions between the US and China have upended the market for certain crops and shifted how the US exerts its influence overseas.
 
Read more: https://www.bloomberg.com/news/articles/2025-12-08/us-farmers-say-12-billion-bailout-won-t-end-industry-slump 

See omnystudio.com/listener for privacy information.

A Fifth-Generation Farmer on Trump’s $12B Bailout

On Wednesday, the Federal Open Market Committee cut rates by 25-basis points. It was the scenario a lot of close watchers of the Federal Reserve expected — but what comes after this Fed Meeting is an open question.
 
With President Trump poised to name Chair Jerome Powell’s replacement by early 2026, both markets and the Federal Reserve itself could start to look to Trump’s nominee for guidance. Kevin Hassett has emerged as the front-runner for the role, who currently serves as director on Trump’s Council of Economic Advisers.
 
On Today’s Big Take podcast, Bloomberg Economics’ Chief US Economist Anna Wong joins host Sarah Holder to break down the economic impact of the latest rate cut and what the Federal Reserve could look like next year if Hassett is nominated to succeed Powell.
 
Read more: Fed Cuts Rates With Three Dissents, Projects One Cut in 2026

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The Fed Just Cut Rates Again. Here’s What’s Ahead for 2026

The US tariff war with China sent American companies scrambling to find alternative manufacturing hubs. India looked promising until the White House upended everything. 
 
On today’s Big Take Asia podcast, K. Oanh Ha heads to India, where she goes inside two toy factories scrambling to adapt to Washington’s shifting trade policies. How sky-high tariffs are undercutting India’s ambitions to take China’s crown as the world’s factory floor and forcing American manufacturers to make a tough choice. 
 
Read more: Cutting Ties With China Is Harder Than Companies Expected
 
Further listening: An American Toymaker Struggles to Break Up With China
The American Toymaker Suing Trump Over Destructive Tariffs

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India Wanted to Become The World’s Toymaker. Then Tariffs Happened

After last month’s passage of the Epstein Files Transparency Act, the US Department of Justice is on the clock to release an enormous cache of documents related to convicted sex trafficker Jeffrey Epstein.
 
So what could be in the files? And what might the government hold back? 
 
On today’s Big Take, host David Gura is joined by Bloomberg investigative reporter Jason Leopold, who specializes in making government documents public and co-hosts Bloomberg’s Disclosure podcast. They talk through how the release could play out and how to parse the files once they’re available.
 
Subscribe to Jason’s FOIA Files newsletter and Disclosure podcast

See omnystudio.com/listener for privacy information.

What to Expect in the DOJ Epstein Files Release

Salman Rushdie was nearly killed when he was stabbed 15 times on stage in upstate New York in 2022. His injuries were so severe that he lost an eye. It was an attack that came decades after he was first subjected to death threats over his novel, The Satanic Verses.

Once he had recovered, he found he was unable to write fiction. However, after publishing an account of what happened to him, the stories returned, with five brought together in his latest book, The Eleventh Hour.

In this conversation with Mishal Husain, Rushdie talks about free speech, the family connection they both share and the places he’s called home, from India to Britain and the US. 

02:30 - “Don’t waste your time”
04:40 - Writing as a form of optimism
05:00 - Starting out as a writer 
08:00 - Meeting E.M. Forster as a teenager
10:00 - “You write the story to find out what story you’re writing”
11:15 - Writing Midnight’s Children 
12:46 - The family connection between Salman Rushdie and Mishal Husain
14:35 - The women in the family
16:00 - Getting together as a family
17:55 - Returning to India to write about childhood
20:30 - Reclaiming India 
22:55 - India today and Prime Minister Modi
24:24 - “If you’re paying attention you see things coming”
24:50 - The family reacts to Midnight’s Children
26:44 - A farewell to India? 
28:45 - Before and after the fatwa
31:30 - Defending free speech 
32:25 - Banning books in the US
34:30 - Zohran Mamdani’s campaign
38:50 - The next novel 
40:25 - “I’m a bit clumsier”

Watch this podcast here: https://www.youtube.com/playlist?list=PLe4PRejZgr0Ns_wjGlmjlPz0cded0nTYS
 
You can find the written version of this interview with Mishal’s notes on Bloomberg Weekend: https://www.bloomberg.com/latest/weekend-interview
 
Contact The Mishal Husain Show mishalshow@bloomberg.net
 
Subscribe today on Apple Podcasts and Spotify.

See omnystudio.com/listener for privacy information.

Weekend Listen: Salman Rushdie Isn’t Afraid of Free Speech

At the height of the Covid-19 pandemic, the US government stepped in with aid to keep mass transit agencies afloat. But that money is running out and ridership hasn’t rebounded.

On today’s Big Take podcast, Bloomberg’s Sri Taylor and Aaron Gordon join host David Gura to discuss why advocates now fear many transit systems are on the verge of a so-called “death spiral” — a vicious cycle of less funding, low ridership and cuts to services that could impact everyone’s commute.
 
Read more: A $6 Billion Shortfall Has US Mass Transit Facing a Death Spiral
 
 

See omnystudio.com/listener for privacy information.

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